Scientific Program

Conference Series Ltd invites all the participants across the globe to attend 3rd Global Experts Meeting on Infectious Diseases Bangkok, Thailand.

Day 1 :

Keynote Forum

Huang Wei Ling

Medical Acupuncture and Pain Management Clinic, Brazil

Keynote: What Do We Need To Know To Prevent And Control Nosocomial Infections Completely?

Time : 09:50-10:30

Conference Series Infectious Diseases Meet 2020 International Conference Keynote Speaker Huang Wei Ling photo
Biography:


Huang Wei Ling, born in Taiwan, raised and graduated in medicine in Brazil, specialist in infectious and parasitic diseases, a General Practitioner and Parenteral and Enteral Medical Nutrition Therapist. Once in charge of the Hospital Infection Control Service of the City of Franca’s General Hospital, she was responsible for the control of all prescribed antimicrobial medication and received an award for the best paper presented at the Brazilian Hospital Infection Control Congress in 1998. Since 1997, she has been presenting her work worldwide, working with the approach and treatment of all diseases of all systems of the human body in a holistic way, with treatment guided through the teachings of Traditional Chinese Medicine and Hippocrates.

Abstract:

Introduction: Nosocomial infections are a widespread problem around the world. Nowadays, only 1/3 of nosocomial infections can be prevented with the Infection Control Programs. The other 2/3 cannot be prevented. In the USA, 31 billions of dollars are spent in the treatment of nosocomial infections per year.  Purpose: The purpose of this study is to demonstrate how this 2/3 of nosocomial infections could be controlled with the use ancient medicines reasoning, such as Traditional Chinese Medicine and Hippocrates theories. Another goal is to make evident the possible economy to healthcare when using these techniques and tools in the treatment of nosocomial infections. Methods: The methodology used was a review of studies, such as those presented by Hippocrates (“Natural forces within us are the true healers of disease.”), as well as others from oriental medicines, which comprehend the disease as originated from three factors: external (exposure to cold, heat, humidity, wind and dryness), internal (emotional) and dietary. Findings: When comprehending the patient in a broader view, considering the energy imbalances of Yin, Yang, Qi, Blood and Heat retention and preventing invasion of external factors, it is possible to control and prevent better more nosocomial infections.  Conclusion: The 2/3 of not controlled nosocomial infections cannot be prevented because of the reasoning used in the treatment of infections in Western Medicine. When using ancient oriental medicines reasoning, a different thinking can be used. According to Einstein, “We cannot solve our problems with the same thinking we used when we created them.”

 

Conference Series Infectious Diseases Meet 2020 International Conference Keynote Speaker Mark Liles photo
Biography:

Mark Liles is currently working as a Microbiologist in the Department of Biological Sciences, Auburn University. He has completed his Bachelors in Biology from Tulane University and PhD in Microbiology from Northwestern University. He has published over 100 peer-reviewed journal articles, over 150 published abstracts and is an inventor on five awarded patents with other patents pending. He Co-founded the Biotechnology company Varigen Biosciences and serves as President of the company.

Abstract:

A clonal population of hyper virulent Aeromonas hydrophila (vAh) has caused the loss of over 10 million kilograms of farmed catfish across the southeastern United States since 2009. Phylogenomic analyses suggest that U.S. catfish isolates emerged from the importation of Asian carp, with outbreaks of A. hydrophila in carp species documented in China since 1989. An ongoing worldwide survey of A. hydrophila isolates revealed that vAh strains have disseminated to multiple countries and can infect diverse fish hosts. We developed two strategies for vAh control, using either probiotic bacteria or an attenuated vaccine. Probiotic studies: We identified Bacillus spp. strains that have the ability to reduce fish mortality due to multiple bacterial pathogens, including vAh. The effect of probiotic-amended feed (106–107 CFU spores/g feed) over 10 or more weeks on catfish growth performance indicated that B. velezensis AP193 induced a mean 9-14% increase in growth compared to control fish and significantly reduced mortality (3%) when challenged with vAh compared to control fish (60% mortality).
Vaccine studies: Comparative genomic analysis of vAh strains from the US and China identified many genetic loci that are uniquely present in vAh strains, including a novel O-antigen biosynthesis gene cluster. Genetic knockouts in the gfc operon responsible for O antigen capsule assembly were found to attenuate vAh virulence, reduce biofilm formation and affect protein secretion. Furthermore, a gfcD mutant was observed to induce an adaptive immune response that protected catfish from challenge with wild-type vAh in aquaria and pond studies.

Keynote Forum

Prof. Mark Liles

Auburn University, Department of Biological Sciences,Auburn, AL, USA

Keynote: The global spread, pathogenesis and control measures for hypervirulent Aeromonas hydrophila in warm water fish species
Biography:

Prof. Mark Liles is microbiologist in the Department of Biological Sciences, Auburn University.  He has a B.S. in Biology from Tulane University, a Ph.D. in Microbiology from Northwestern University (1998), and conducted postdoctoral research at the University of Wisconsin-Madison in the labs of Prof. Jo Handelsman and Prof. Bob Goodman. Over the past 30+ years in science, he has developed methods for community genomic (“metagenomic”) analysis of complex microbial communities and developed treatments for the control of disease in agriculture, aquaculture and human medicine. He has published over 100 peer-reviewed journal articles, over 150 published abstracts and is an inventor on five awarded patents with other patents pending. He co-Founded the biotechnology company Varigen Biosciences and serves as President of the company.

 

Abstract:

A clonal population of hypervirulent Aeromonas hydrophila (vAh) has caused the loss of over 10 million kilograms of farmed catfish across the southeastern United States since 2009. Phylogenomic analyses suggest that U.S. catfish isolates emerged from the importation of Asian carp, with outbreaks of A. hydrophila in carp species documented in China since 1989. An ongoing worldwide survey of A. hydrophila isolates revealed that vAh strains have disseminated to multiple countries and can infect diverse fish hosts. We developed two strategies for vAh control, using either probiotic bacteria or an attenuated vaccine. Probiotic studies: We identified Bacillus spp. strains that have the ability to reduce fish mortality due to multiple bacterial pathogens, including vAh. The effect of probiotic-amended feed (106 – 107 CFU spores/g feed) over 10 or more weeks on catfish growth performance indicated that B. velezensis AP193 induced a mean 9-14% increase in growth compared to control fish and significantly reduced mortality (3%) when challenged with vAh compared to control fish (60% mortality). Vaccine studies: Comparative genomic analysis of vAh strains from the US and China identified many genetic loci that are uniquely present in vAh strains, including a novel O-antigen biosynthesis gene cluster. Genetic knockouts in the gfc operon responsible for O antigen capsule assembly were found to attenuate vAh virulence, reduce biofilm formation and affect protein secretion. Furthermore, a gfcD mutant was observed to induce an adaptive immune response that protected catfish from challenge with wild-type vAh in aquaria and pond studies.

 

Keynote Forum

Dr Swapnil Gautam

prestigious institute of Grant Medical College & Sir J J Group of Hospitals, Mumbai

Keynote: Current status and Management : Indian Perspective
Biography:

Dr Swapnil Gautam has received MD qualification from the prestigious institute of Grant Medical College & Sir J J Group of Hospitals, Mumbai. He has a rare distinction of MRCP from three different places – London, Glasgow and Edinburgh. He has obtained his specialization in infectious diseases from the world recognized London School of Hygiene & Tropical Medicine and also from the University of New South Wales, Sydney. He is an eminent speaker at local, national and international level academic platforms.

 

Abstract:

Dengue is a flavivirus, transmitted by the mosquito Aedes aegypti. WHO had identified it as one of the neglected tropical diseases in 2010. The maximum disease burden due to dengue is in south east Asian and western pacific countries. India is an endemic country for dengue. Every year during and after monsoon, the number of dengue cases peak. The small and transient water collections along with appropriate temperature range and relative humidity leads to higher vector density. There are four dengue virus serotypes – DENV 1 – 4. The infection with any one serotype provides lifelong immunity to that particular serotype only. The vector breeds mostly in domestic man made water storage objects. The female Ae. aegypti becomes infected with dengue virus after consumption of blood meal from a person suffering from the disease. The virus is transmitted by introduction of saliva into the wound of the person bitten. The secondary infections are generally seem to be the worse. The different pathological mechanisms involve T cell mediated antibody response cross reacting with vascular endothelium along with release different cytokines and mediators. There is an increase in capillary permeability which leads plasma leakage and shock. The functional disturbance of endothelial glycocalyx also happens transiently. There is thrombocytopenia and coagulopathy. Majority of the persons, infected with the dengue virus remain asymptomatic. Those who are symptomatic, may develop severe manifestations. These are multiorgan involvement, bleeding and intractable shock. The different grades are – dengue fever (DF), dengue hemorrhagic fever ( DHF ). DHF III and DHF IV are dengue shock syndrome ( DSS ). The different phases of illness include – febrile phase, critical phase and convalescent phase.The febrile phase is characterized by fever, joints and muscle pain. There may be presence of a rash during stage. The critical phase is where most of the complications occur. This phase comes 3 to 4 days after onset of fever. Dengue can lead involvement of multiple organ systems and coagulopathy. There have been cases of hemophagocytic lymphohistiocytosis  due to dengue. The management of dengue involves fluid correction, symptomatic treatment and correction of complications. The vaccines haven’t been introduced in India.

 

Keynote Forum

Hafez Mirzanezhad asl

Department of medical Parasitology and microbiology, Ardabil University of Medical Sciences (Arums), Iran

Keynote: Survey of human alveolar and cystic echinococcosis rates based on ELISA and portable ultrasound in Moghan, northwestern Iran
Biography:

Background: Alveolar echinococcosis (AE) and cystic echinococcosis (CE) are severe helminthic zoonoses. Echinococcus multilocularis (causative agent of AE) is widely distributed in the northern hemisphere where it is typically maintained in a wild animal cycle including canids as definitive hosts and rodents as intermediate hosts.

Methods: This study was conducted to determine the spread of human AE and CE disease among tribes, livestock breeders and farmers in the Moghan plain. Knowledge gains were compared at the 6th and 12th months after study, elementary and guidance courses, and higher education with a basic level of education Prevalence of infection.

Results: The most important risk factors were excessive consumption of wild vegetables and the use of spring water. Keeping the dog in the yard was the third risk factor. Results were analyzed using logistic regression and SPSS 21 software. From 2453 serum samples, 21 samples were positive for AE 0.79% with Em2+ Ag. The prevalence was higher in men than women (1.24% vs. 0.6%). Age range of 40-59 years' highest infection rates. About CE, for Ag-5 and Ag-B, 172(6.4%) & 178 (6.7%) serum samples were positive, respectively. CE was higher in women than men (8.52% vs. 5.6%). The age range 40-59 years presented the highest infection rates.

Conclusion: Due to the high prevalence of Echinococcosis in these areas, it is necessary to control, prevent and combat these diseases

Abstract:

has completed his PhD at the age of 36 years from Iran University of Medical Sciences, IRAN. He is the FACULTY MEMBER OF ARDABIL UNIVERSITY OF MEDICAL SCIENCE. I have published more than 14 papers in reputed journals and has been serving as an editorial board member of repute. (Up to 100 words)

  • International Child Health and Paediatric Infections
Location: Bangkok, Thailand

Chair

International Child Health and Paediatric Infections

Session Introduction

Wei Ling Huang

Wei Ling Huang, Medical Acupuncture and Pain Management Clinic, Brazil

Title: Can hospital Osteomyelitis be treated without the use of antibiotics?

Time : 11:45-12:30

Speaker
Biography:

Dr. Huang Wei Ling, born in Taiwan, raised and graduated in medicine in Brazil, specialist in infectious and parasitic diseases, a General Practitioner and Parenteral and Enteral Medical Nutrition Therapist. Once in charge of the Hospital Infection Control Service of the City of Franca’s General Hospital, she was responsible for the control of all prescribed antimicrobial medication and received an award for the best paper presented at the Brazilian Hospital Infection Control Congress in 1998. Since 1997, she works with the approach and treatment of all diseases of all systems of the human body in a holistic way, with treatment guided through the teachings of Traditional Chinese Medicine and Hippocrates. Since 2007, she is also speaker in several congress worldwide in different medical specialties, all aiming to pass the idea of treating patients in the energy level and not only the symptom. 

Abstract:

Statement of the problem: Osteomyelities is a bone infection which can reach the bone by traveling through the bloodstream or spreading from nearby tissue. Once considered an incurable condition, osteomyelitis can sometimes be successfully treated by surgery to remove parts of the bone that have died and antibiotic treatment. The purpose of this study is to show why the treatment of osteomyelitis is so difficult and often considered incurable. We show that to reach improvement, we need to look at the patient as a whole, not only at the disease. The methodology is presented in two case reports: the first one showing an infection resulting from knee fracture surgery done after a motorcycle accident that had been treated with the use of a large spectrum of antibiotics without any improvement. The second case was another hospital osteomyelitis after a postprosthesis infection in the knee which had been treated profusely with antibiotics with no improvement. Findings: Both cases were treated successfully taking out all the anti-inflammatory and antibiotic drugs, together with the use of Chinese dietary counselling, auricular acupuncture associated with apex ear bloodletting, in order to balance Yin, Yang, Qi, Blood energy and removing Heat retention following the theories of Traditional Chinese Medicine. In these two cases, the osteomyelitis symptoms were being maintained exactly by the aggressive intake of antibiotics, and its side effects, according to TCM reasoning. Conclusion: According to these two case reports, hospital osteomyelitis can be treated without the use of antibiotics.

Speaker
Biography:

Tiwaporn Junkhaw has completed her PhD in 2016 from College of Public Health Science, Chulalongkorn University, Thailand. Her research interests in areas include health policy, community health and health law enforcement. Currently, she is a Technical Public Health Officer, Lecturer and Lawyer in the Provincial Public Health Office, North of Thailand. Her background was Pharmacy Technician and Epidemiologist with TB Management.

Abstract:

Introduction & Aim: The incidence of Diabetes Mellitus (DM) is increasing worldwide and is a major public health problem, including Thailand due to its high prevalence and its chronic complications. A few studies were applied health literacy to develop health promotion programs for older adult and elderly patients such as multi-engagement for DM management and quality of life. Moreover, commonly held view is that multicenter interventions are more effective approach in improving glycated hemoglobin (HbA1c) controlling and influencing quality of life. The aim of this study was to examine the effect of the Multifaceted Healthy Coaching Program to improve HbA1c and quality of life among older adult and elderly type-2 diabetics semi-urban dweller, Bangkok, Thailand. Methods: A single-blinded randomized control trial, recruited 174 diabetics patients from Public Health Center 61 in suburb of Bangkok, with HbA1c level & gt; 7.0% and low to moderate health literacy were randomized to receive Multifaceted Healthy Coaching Program (n=40) or usual care (n=40) over 6 months. The intervention group participants received DM management booklet, diary records for healthy behaviors group education, short message (SMS) reminder for healthy behaviors and drug adherence and individual telephone counselling monthly while the usual care group did not receive any intervention. Regarding to statistical analysis for improved research outcomes at baseline to 6 months as health literacy, the diabetes knowledge, selfefficacy, self-care activity, HbA1c level and quality of life were used paired t-test and independent t-test. As for changing in Fasting Plasma Glucose (FPG) from baseline, 3 and 6 months were applied repeated ANOVA measurement. Result: At baseline in both groups were similar in sociodemographic characteristics, duration of diabetic history and outcome measurement. After implementing Multifaceted Healthy Coaching Program in 6 months, overall of health literacy and six components of health literacy were significantly improved in the intervention group compared to control group (p< 0.01). Additionally, intervention group also had significantly greater diabetes knowledge, self-efficacy and self-care activity than control group (p < 0.01). At the end of program revealed that the percentage reduction of HbA1c level was greater in intervention group (p<0.01) and the achievement of Multifaceted Healthy Coaching program showed significant improvement in quality of life among the intervention group when compared to the control group (P<0.01). Conclusion: Patients with type-2 diabetes perceive Multifaceted Healthy Coaching as an acceptable intervention in their ongoing care. Overall, this program in primary care appears to lead to significant benefits for patients from low health literacy with poorly controlled type-2 diabetes.

Wei Ling Huang

Medical Acupuncture and Pain Management Clinic, Brazil

Title: Can we treat urinary tract infections without using any antibiotics?

Time : 12:45-13:15

Speaker
Biography:

Huang Wei Ling has completed her Graduation in Medicine in Brazil and Specialist in Infectious and Parasitic Diseases, and also General Practitioner and
Parenteral and Enteral Medical Nutrition Therapist.

Abstract:

Several studies point out urinary tract infections as a widely common pathology worldwide. In Traditional Chinese Medicine the physiopathology of the disease is kidney yin deficiency, blood deficiency and heat retention. The objective of this study is to demonstrate the possibility of treating urinary tract infections without using antibiotics. The interpretation and analysis of recent articles regarding the treatment of urinary tract infections in Western medicine, Traditional Chinese medicine and Hippocratic medicine. This is a description and analysis of two case-reports. The first case report is a 75-year-old woman
and the second case report is a 45-year-old female patient both with symptoms of dysuria and diagnosed with urinary tract infection, with positive urine culture for bacteria. The patients presented improvement of the symptoms and urine cultures positive for bacteria before the treatment and negative after the treatment only with acupuncture, Chinese dietary counseling and apex ear bloodletting, not requiring antibiotics use in neither of the cases. Both patients presented complete improvement of urinary tract infections with one session of auricular acupuncture with apex ear bloodletting. The result for both cases appeared in a few days. It is possible to treat urinary tract infections without using antibiotics, according to these two case reports. For this aim, it is important to treat the patient through an integral pathway, focusing the treatment in the energy disturbances, the underlying cause of the symptoms.

  • Microbiology and Bacteriology
Location: Bangkok, Thailand
Speaker
Biography:

Huang Wei Ling, born in Taiwan, raised and graduated in medicine in Brazil, specialist in infectious and parasitic diseases, a General Practitioner and Parenteral and Enteral Medical Nutrition Therapist. Once in charge of the Hospital Infection Control Service of the City of Franca’s General Hospital, she was responsible for the control of all prescribed antimicrobial medication and received an award for the best paper presented at the Brazilian Hospital Infection Control Congress in 1998. Since 1997, she has been presenting her work worldwide, working with the approach and treatment of all diseases of all systems of the human body in a holistic way, with treatment guided through the teachings of Traditional Chinese Medicine and Hippocrates. 

Abstract:

Introduction: Several studies point out urinary tract infections as a widely common pathology worldwide. In Traditional Chinese Medicine the physiopathology of the disease is Kidney Yin deficiency, Blood deficiency and Heat Retention.

Purpose: The purpose of this study is to demonstrate the possibility of treating urinary tract infections without using antibiotics.

Methods: The interpretation and analysis of recent articles regarding the treatment of urinary tract infections in Western Medicine, Traditional Chinese Medicine and Hippocratic Medicine. The description and analysis of two case-reports. The first from a 75-year-old woman and the second from a 45-year-old female patient both with symptoms of dysuria and diagnosed with urinary tract infection, with positive urine culture for bacteria.

Results: All patients presented improvement of the symptoms and urine cultures positive for bacteria before the treatment and negative after the treatment only with acupuncture, Chinese dietary counseling and apex ear bloodletting, not requiring antibiotics use in neither of the cases. Both patients presented complete improvement of urinary tract infections with one session of auricular acupuncture with apex ear bloodletting. The result for both cases appeared in a few days.

Conclusion: It is possible to treat urinary tract infections without using antibiotics, according to these two case reports. For this aim, it is important to treat the patient through an integral pathway, focusing the treatment in the energy disturbances, the underlying cause of the symptoms.

 

  • Immunization and Infection Control
Location: Bangkok, Thailand

Session Introduction

Huang Wei Ling

MD, Medical Acupuncture and Pain Management Clinic

Title: Can we Treat Urinary Tract Infections Without Using Any Antibiotics?
Speaker
Biography:

Huang Wei Ling, born in Taiwan, raised and graduated in medicine in Brazil, specialist in infectious and parasitic diseases, a General Practitioner and Parenteral and Enteral Medical Nutrition Therapist. Once in charge of the Hospital Infection Control Service of the City of Franca’s General Hospital, she was responsible for the control of all prescribed antimicrobial medication and received an award for the best paper presented at the Brazilian Hospital Infection Control Congress in 1998. Since 1997, she has been presenting her work worldwide, working with the approach and treatment of all diseases of all systems of the human body in a holistic way, with treatment guided through the teachings of Traditional Chinese Medicine and Hippocrates. 

Abstract:

Introduction: Several studies point out urinary tract infections as a widely common pathology worldwide. In Traditional Chinese Medicine the physiopathology of the disease is Kidney Yin deficiency, Blood deficiency and Heat Retention.

Purpose: The purpose of this study is to demonstrate the possibility of treating urinary tract infections without using antibiotics.

Methods: The interpretation and analysis of recent articles regarding the treatment of urinary tract infections in Western Medicine, Traditional Chinese Medicine and Hippocratic Medicine. The description and analysis of two case-reports. The first from a 75-year-old woman and the second from a 45-year-old female patient both with symptoms of dysuria and diagnosed with urinary tract infection, with positive urine culture for bacteria.

Results: All patients presented improvement of the symptoms and urine cultures positive for bacteria before the treatment and negative after the treatment only with acupuncture, Chinese dietary counseling and apex ear bloodletting, not requiring antibiotics use in neither of the cases. Both patients presented complete improvement of urinary tract infections with one session of auricular acupuncture with apex ear bloodletting. The result for both cases appeared in a few days.

Conclusion: It is possible to treat urinary tract infections without using antibiotics, according to these two case reports. For this aim, it is important to treat the patient through an integral pathway, focusing the treatment in the energy disturbances, the underlying cause of the symptoms.

 

  • Tuberculosis and Pneumonia
Location: Bangkok, Thailand

Chair

Tuberculosis and Pneumonia

Speaker
Biography:

Dr. Khan has completed his graduate degree in medicine (MD) from Kng Edward Medical College. He obtained Masters in Public Health (MPH) from New York Mecial College, with specialized training in tropical medicine and obtained Diploma in Tropical Medicine (DTMH). Dr. Khan started his career as research clinical epidemiologist at Kingsbrook Jewish Medical Center, Brooklyn, New York. He worked as Direcor of Hospital Epidemiology and Infection Control at Long Island College of State University of New York and Director of Epidemiology and Occupational Health at Lourdes Health System in New Jersey. Dr. Khan worked as Director of Public Health and Communicable Disease at WHO Collaborative Infection ControlCenter in Saudi Arabia. Currently he is system Director of Epidemiology and Infection Control at major healthcare system in south west florida. He consulted for Joint Commission International and presented at international conferences.

Abstract:

We introduces a collaborative, multidisciplinary effort, to engage physicians, nursing, allied providers and other care providers in a process that could be conducive for proactive implementation of the Clinical Collaborating Council action plan at a “grass root level” of care at units at each of the Lee Health facilities. Program designed to reach our front line staff by formation of IP Process Improvement teams (IPPI) at each of our campuses. The long term objectives of our initiative was by creating a “mini IP”/champion on each unit , developing magnate program for inspiring IP’s and IP engagement, empowerment, and accountability at each campus. Main goals was to conduct case findings in order to determine status and opportunities for improvement in the treatment and prevention of infections, to monitor the process of care at the bedside, provide coaching and teaching, and analyze the clinical epidemiology data pertaining to process improvement initiatives, decrease morbidity/mortality related to infections and pre-infectious events and identify resources for prevention and control of infections. Effectiveness and outcome were evaluated on an ongoing basis. We redesign our interventions as recommended by our team. A system dashboard will be shared with Lee Health leadership on activities of IPPI of each hospital by IP coordinator. Each quarter hospitals presented the success story and work to the hospital leadership. Effective coordinated process resulted 85% implementation of our care bundles with eduction of device related infection, c. difficile and MRSA

 

  • Vaccine Immunology and Therapeutics
Location: Bangkok, Thailand
Speaker
Biography:

I am Md. Naushad khan doctoral fellow in Department of Biotechnology, School of Chemical and Life Sciences, Jamia Hamdard University, India. I did complete the Master of Philosophy from the Jamia Millia Islamia University, India. Currently I am publishing the four papers and participate in the National and International Conferences. During my participant I present the poster as well as oral deliberate lectures.

Abstract:

Chikungunya virus (CHIKV) an arthropod-borne alphavirus is responsible for the emerging disease chikungunya fever. Chikungunya symptoms show fever, joint pain, nausea, muscle pain, and rash. Arthralgia is a major symptom of this disease and some patients recover early while others suffer for a very long time. To describe CHIKV genetic diversity and the clinical outcome from suspected patients attended at a Jamia Hamdard Institute of Medical Sciences (JHIMS) hospital in New Delhi (North India) from 2016.Whole genome sequences (WGS) of CHIKV have carried out three RT-PCR positive samples and assessed by phylogenetic analysis, in silico study for comparison of physiological properties of CHIKV proteins, antigenicity and B cell epitope prediction.  WGS of three CHIKV and comparison to S27 East/Central/South African (ECSA) strain of CHIKV are reported here. Of the 325 subjects, 118 (36.30%) were recorded positive by either RT-PCR or IgM ELISA. Clinical features of CHIKV of rash 47 (39.83%), joint pain 78 (66.10%), joint swelling 61 (51.69%) and some other symptoms such as headache, vomiting, etc.  Analysis of WGS showed the maximum number of mutations in a structural gene compared to the nonstructural gene. The study gives special importance for continuous surveillance of disease burden using multiple diagnostic tests, characterization, changes in vector-pathogen similarity and interaction of host-pathogen for development of suitable vaccine candidate and antivirals.

  • Neuro Infectious Diseases
Location: Bangkok, Thailand

Session Introduction

Mukherjee SK

Assistant Professor, Department of Pediatric Neurosurgery, Dhaka

Title: ToRCH positivity amongst children presenting with congenital hydrocephalus in Bangladesh
Speaker
Biography:

Dr. Sudipta Kumer Mukherjee, Assistant Professor, Department of Pediatric Neurosurgery, National Institute of  Neurosciences & Hospital, Sher-E-Bangla Nagar, Dhaka-1207

Abstract:

Introduction: ToRCH   is an acronym for four congenital infections that are sometimes difficult to distinguish: Toxoplasmosis, Rubella, Cytomegalovirus, and Herpes Simplex Virus. This group of organisms produces serious CNS and other infections, which are potentially preventable and treatable.

Methods: Neonates and infants with hydrocephalus (N = 65) identified via the outpatient department of the National Institute of Neurosciences and Hospital (NINS&H), were prospectively screened for ToRCH antibodies.  Patients with hydrocephalus secondary to tumor, trauma, hemorrhage, arachnoid cyst, and Dandy Walker Malformation were excluded from this study.

Results:  Evidence of 75.38% of patients was positive for ToRCH antibodies. T. Gondii IgG 18.5%, CMV IgM 9.2 %, CMV Ig G 47.7%, Rubella, and Herpesvirus 1& 2 antibodies were also identified.

Conclusion: The vast majority of cases of idiopathic neonatal hydrocephalus at one institution were post-infectious in etiology and related to ToRCH infections. Many of these cases could have been prevented with improved maternal education, screening and treatment. While this single institution study may not be representative of the entire population, further study and implementation of a standardized screening protocol would likely benefit this population.

 

  • Emerging Infectious Disease Update
Location: Bangkok, Thailand
Speaker
Biography:

Dr. Khan has completed his graduate degree in medicine (MD) from Kng Edward Medical College. He obtained Masters in Public Health (MPH) from New York Mecial College, with specialized training in tropical medicine and obtained Diploma in Tropical Medicine (DTMH). Dr. Khan started his career as research clinical epidemiologist at Kingsbrook Jewish Medical Center, Brooklyn, New York. He worked as Direcor of Hospital Epidemiology and Infection Control at Long Island College of State University of New York and Director of Epidemiology and Occupational Health at Lourdes Health System in New Jersey. Dr. Khan worked as Director of Public Health and Communicable Disease at WHO Collaborative Infection ControlCenter in Saudi Arabia. Currently he is system Director of Epidemiology and Infection Control at major healthcare system in south west florida. He consulted for Joint Commission International and presented at international conferences.

Abstract:

South West Florida red tides are a natural phenomenon caused by dense aggregations of single cell or several species of unicellular organisms. Patches of discolored water, dead or dying fish, and respiratory irritants in the air often characterize these algal blooms. In humans, two distinct clinical entities, depending on the route of exposure, are associated with exposure to the Florida red tide toxins (particularly the brevetoxins).

The two known forms of red tide toxins-associated clinical entities in humans first characterized in Florida are an acute gastroenteritis with neurologic symptoms after ingestion of contaminated shellfish (i.e. NSP) and an apparently reversible upper respiratory syndrome after the inhalation of the aerosols of the dinoflagellate and their toxins. Red Tide Symptoms: IRRITATED EYES AND THROAT, COUGH, RUNNY NOSE TIGHTNESS OF CHEST OR WHEEZING,, SHORTNESS OF BREATH. Blue Green Algae Symptoms: Direct contact with the organism or breathing of toxin, Rash, Stomach cramps, Nausea, Diarrhea , Vomiting, Liver toxicity, Nervous system effects, Irritation of eyes, notes, throat.. Blue Green Algae is Cyanobacteria can live in freshwater,  saltwater or brackish water, most blue-green algae do not produce chemicals harmful to humans or animals, some types make natural substances called cyantotoxins. Safety concerns refrain form recreational, Fish caught near the bloom may have high accumulation of cyanotoxins in the organs