Scientific Program

Conference Series Ltd invites all the participants across the globe to attend 3rd Global Experts Meeting on Infectious Diseases Bangkok, Thailand.

Day 1 :

Keynote Forum

Huang Wei Ling

Medical Acupuncture and Pain Management Clinic, Brazil

Keynote: What Do We Need To Know To Prevent And Control Nosocomial Infections Completely?

Time : 09:50-10:30

Conference Series Infectious Diseases Meet 2020 International Conference Keynote Speaker Huang Wei Ling photo
Biography:


Huang Wei Ling, born in Taiwan, raised and graduated in medicine in Brazil, specialist in infectious and parasitic diseases, a General Practitioner and Parenteral and Enteral Medical Nutrition Therapist. Once in charge of the Hospital Infection Control Service of the City of Franca’s General Hospital, she was responsible for the control of all prescribed antimicrobial medication and received an award for the best paper presented at the Brazilian Hospital Infection Control Congress in 1998. Since 1997, she has been presenting her work worldwide, working with the approach and treatment of all diseases of all systems of the human body in a holistic way, with treatment guided through the teachings of Traditional Chinese Medicine and Hippocrates.

Abstract:

Introduction: Nosocomial infections are a widespread problem around the world. Nowadays, only 1/3 of nosocomial infections can be prevented with the Infection Control Programs. The other 2/3 cannot be prevented. In the USA, 31 billions of dollars are spent in the treatment of nosocomial infections per year.  Purpose: The purpose of this study is to demonstrate how this 2/3 of nosocomial infections could be controlled with the use ancient medicines reasoning, such as Traditional Chinese Medicine and Hippocrates theories. Another goal is to make evident the possible economy to healthcare when using these techniques and tools in the treatment of nosocomial infections. Methods: The methodology used was a review of studies, such as those presented by Hippocrates (“Natural forces within us are the true healers of disease.”), as well as others from oriental medicines, which comprehend the disease as originated from three factors: external (exposure to cold, heat, humidity, wind and dryness), internal (emotional) and dietary. Findings: When comprehending the patient in a broader view, considering the energy imbalances of Yin, Yang, Qi, Blood and Heat retention and preventing invasion of external factors, it is possible to control and prevent better more nosocomial infections.  Conclusion: The 2/3 of not controlled nosocomial infections cannot be prevented because of the reasoning used in the treatment of infections in Western Medicine. When using ancient oriental medicines reasoning, a different thinking can be used. According to Einstein, “We cannot solve our problems with the same thinking we used when we created them.”

 

Conference Series Infectious Diseases Meet 2020 International Conference Keynote Speaker Mark Liles photo
Biography:

Mark Liles is currently working as a Microbiologist in the Department of Biological Sciences, Auburn University. He has completed his Bachelors in Biology from Tulane University and PhD in Microbiology from Northwestern University. He has published over 100 peer-reviewed journal articles, over 150 published abstracts and is an inventor on five awarded patents with other patents pending. He Co-founded the Biotechnology company Varigen Biosciences and serves as President of the company.

Abstract:

A clonal population of hyper virulent Aeromonas hydrophila (vAh) has caused the loss of over 10 million kilograms of farmed catfish across the southeastern United States since 2009. Phylogenomic analyses suggest that U.S. catfish isolates emerged from the importation of Asian carp, with outbreaks of A. hydrophila in carp species documented in China since 1989. An ongoing worldwide survey of A. hydrophila isolates revealed that vAh strains have disseminated to multiple countries and can infect diverse fish hosts. We developed two strategies for vAh control, using either probiotic bacteria or an attenuated vaccine. Probiotic studies: We identified Bacillus spp. strains that have the ability to reduce fish mortality due to multiple bacterial pathogens, including vAh. The effect of probiotic-amended feed (106–107 CFU spores/g feed) over 10 or more weeks on catfish growth performance indicated that B. velezensis AP193 induced a mean 9-14% increase in growth compared to control fish and significantly reduced mortality (3%) when challenged with vAh compared to control fish (60% mortality).
Vaccine studies: Comparative genomic analysis of vAh strains from the US and China identified many genetic loci that are uniquely present in vAh strains, including a novel O-antigen biosynthesis gene cluster. Genetic knockouts in the gfc operon responsible for O antigen capsule assembly were found to attenuate vAh virulence, reduce biofilm formation and affect protein secretion. Furthermore, a gfcD mutant was observed to induce an adaptive immune response that protected catfish from challenge with wild-type vAh in aquaria and pond studies.

Keynote Forum

Prof. Mark Liles

Auburn University, Department of Biological Sciences,Auburn, AL, USA

Keynote: The global spread, pathogenesis and control measures for hypervirulent Aeromonas hydrophila in warm water fish species
Conference Series Infectious Diseases Meet 2020 International Conference Keynote Speaker Prof. Mark Liles photo
Biography:

Prof. Mark Liles is microbiologist in the Department of Biological Sciences, Auburn University.  He has a B.S. in Biology from Tulane University, a Ph.D. in Microbiology from Northwestern University (1998), and conducted postdoctoral research at the University of Wisconsin-Madison in the labs of Prof. Jo Handelsman and Prof. Bob Goodman. Over the past 30+ years in science, he has developed methods for community genomic (“metagenomic”) analysis of complex microbial communities and developed treatments for the control of disease in agriculture, aquaculture and human medicine. He has published over 100 peer-reviewed journal articles, over 150 published abstracts and is an inventor on five awarded patents with other patents pending. He co-Founded the biotechnology company Varigen Biosciences and serves as President of the company.

 

Abstract:

A clonal population of hypervirulent Aeromonas hydrophila (vAh) has caused the loss of over 10 million kilograms of farmed catfish across the southeastern United States since 2009. Phylogenomic analyses suggest that U.S. catfish isolates emerged from the importation of Asian carp, with outbreaks of A. hydrophila in carp species documented in China since 1989. An ongoing worldwide survey of A. hydrophila isolates revealed that vAh strains have disseminated to multiple countries and can infect diverse fish hosts. We developed two strategies for vAh control, using either probiotic bacteria or an attenuated vaccine. Probiotic studies: We identified Bacillus spp. strains that have the ability to reduce fish mortality due to multiple bacterial pathogens, including vAh. The effect of probiotic-amended feed (106 – 107 CFU spores/g feed) over 10 or more weeks on catfish growth performance indicated that B. velezensis AP193 induced a mean 9-14% increase in growth compared to control fish and significantly reduced mortality (3%) when challenged with vAh compared to control fish (60% mortality). Vaccine studies: Comparative genomic analysis of vAh strains from the US and China identified many genetic loci that are uniquely present in vAh strains, including a novel O-antigen biosynthesis gene cluster. Genetic knockouts in the gfc operon responsible for O antigen capsule assembly were found to attenuate vAh virulence, reduce biofilm formation and affect protein secretion. Furthermore, a gfcD mutant was observed to induce an adaptive immune response that protected catfish from challenge with wild-type vAh in aquaria and pond studies.

 

Keynote Forum

Dr Swapnil Gautam

prestigious institute of Grant Medical College & Sir J J Group of Hospitals, Mumbai

Keynote: Current status and Management : Indian Perspective
Conference Series Infectious Diseases Meet 2020 International Conference Keynote Speaker Dr Swapnil Gautam  photo
Biography:

Dr Swapnil Gautam has received MD qualification from the prestigious institute of Grant Medical College & Sir J J Group of Hospitals, Mumbai. He has a rare distinction of MRCP from three different places – London, Glasgow and Edinburgh. He has obtained his specialization in infectious diseases from the world recognized London School of Hygiene & Tropical Medicine and also from the University of New South Wales, Sydney. He is an eminent speaker at local, national and international level academic platforms.

 

Abstract:

Dengue is a flavivirus, transmitted by the mosquito Aedes aegypti. WHO had identified it as one of the neglected tropical diseases in 2010. The maximum disease burden due to dengue is in south east Asian and western pacific countries. India is an endemic country for dengue. Every year during and after monsoon, the number of dengue cases peak. The small and transient water collections along with appropriate temperature range and relative humidity leads to higher vector density. There are four dengue virus serotypes – DENV 1 – 4. The infection with any one serotype provides lifelong immunity to that particular serotype only. The vector breeds mostly in domestic man made water storage objects. The female Ae. aegypti becomes infected with dengue virus after consumption of blood meal from a person suffering from the disease. The virus is transmitted by introduction of saliva into the wound of the person bitten. The secondary infections are generally seem to be the worse. The different pathological mechanisms involve T cell mediated antibody response cross reacting with vascular endothelium along with release different cytokines and mediators. There is an increase in capillary permeability which leads plasma leakage and shock. The functional disturbance of endothelial glycocalyx also happens transiently. There is thrombocytopenia and coagulopathy. Majority of the persons, infected with the dengue virus remain asymptomatic. Those who are symptomatic, may develop severe manifestations. These are multiorgan involvement, bleeding and intractable shock. The different grades are – dengue fever (DF), dengue hemorrhagic fever ( DHF ). DHF III and DHF IV are dengue shock syndrome ( DSS ). The different phases of illness include – febrile phase, critical phase and convalescent phase.The febrile phase is characterized by fever, joints and muscle pain. There may be presence of a rash during stage. The critical phase is where most of the complications occur. This phase comes 3 to 4 days after onset of fever. Dengue can lead involvement of multiple organ systems and coagulopathy. There have been cases of hemophagocytic lymphohistiocytosis  due to dengue. The management of dengue involves fluid correction, symptomatic treatment and correction of complications. The vaccines haven’t been introduced in India.

 

Keynote Forum

Hafez Mirzanezhad asl

Department of medical Parasitology and microbiology, Ardabil University of Medical Sciences (Arums), Iran

Keynote: Survey of human alveolar and cystic echinococcosis rates based on ELISA and portable ultrasound in Moghan, northwestern Iran
Conference Series Infectious Diseases Meet 2020 International Conference Keynote Speaker Hafez Mirzanezhad asl  photo
Biography:

Background: Alveolar echinococcosis (AE) and cystic echinococcosis (CE) are severe helminthic zoonoses. Echinococcus multilocularis (causative agent of AE) is widely distributed in the northern hemisphere where it is typically maintained in a wild animal cycle including canids as definitive hosts and rodents as intermediate hosts.

Methods: This study was conducted to determine the spread of human AE and CE disease among tribes, livestock breeders and farmers in the Moghan plain. Knowledge gains were compared at the 6th and 12th months after study, elementary and guidance courses, and higher education with a basic level of education Prevalence of infection.

Results: The most important risk factors were excessive consumption of wild vegetables and the use of spring water. Keeping the dog in the yard was the third risk factor. Results were analyzed using logistic regression and SPSS 21 software. From 2453 serum samples, 21 samples were positive for AE 0.79% with Em2+ Ag. The prevalence was higher in men than women (1.24% vs. 0.6%). Age range of 40-59 years' highest infection rates. About CE, for Ag-5 and Ag-B, 172(6.4%) & 178 (6.7%) serum samples were positive, respectively. CE was higher in women than men (8.52% vs. 5.6%). The age range 40-59 years presented the highest infection rates.

Conclusion: Due to the high prevalence of Echinococcosis in these areas, it is necessary to control, prevent and combat these diseases

Abstract:

has completed his PhD at the age of 36 years from Iran University of Medical Sciences, IRAN. He is the FACULTY MEMBER OF ARDABIL UNIVERSITY OF MEDICAL SCIENCE. I have published more than 14 papers in reputed journals and has been serving as an editorial board member of repute. (Up to 100 words)