Day 2 :
Keynote Forum
Yoshinori HAYAKAWA
Ex-professor, Toin University of Yokohama, Kanagawa-ken
Keynote: Universal Vaccine and Artificial Pandemics by Infectious Attenuated Live Vaccine to Save People from Dangerous New Influenza Pandemic
Biography:
Yoshinori Hayakawa has engaged in medical physics. He developed simultaneous neutron monitoring system for Boron-Neutron-Capture-Therapy. He has measured, first in the world, acoustic pulse generated in the body of treated patient by pulsed proton beam. The phenomenon may be used to monitor dose distribution in patients. He is interested in researches on human wellbeing. He has developed Four Arithmetic Operations with Lines, New Abacus Numerals, and Universal Literacy Alphabet for improving basic education to reduce poverty. These can be observed in youtube without payment. He insists use of plant factory and space-based solar electric power generation against global cooling.
Abstract:
Universal Influenza Vaccine is proposed and under development ( https://www.niaid.nih.gov/diseases-conditions/universal-influenza-vaccine-research ). Universal Vaccine seems not to be payable for many people in developing countries, ( dangerous pandemics usually start at developing countries from bird influenza ). Artificial Pandemics by Infectious Attenuated Live Vaccine are proposed by the Author ( https://www.youtube.com/watch?v=S8XxAsUk3QM ). Ferret nasal mucosa is carcinized using carcinogen for easiness of incubation. Bird influenza virus is attenuated by reverse genetics. The virus is marked by green fluorescent protein. This attenuated virus is sprayed to many cultured cancer cell specimen incubated. In some specimen attenuated virus will mutated to increase in cancer cells, checked by green fluorescence. Then the virus is tested to infect ferret and then human volunteers without serious syndrome. Virus with strongest virus titer to infect ferret is selected as seed virus of infectious attenuated live vaccine. The seed virus will be increased in incubated cancer cells by bioreactors all over the world and sprayed to vulnerable people, e.g., soldiers, students, people in slams, medical staffs, and people engaged in lifeline. Artificial pandemics of dangerous virus as H7N9, H5N1 etc., are to be created serially with few years interval. Artificial pandemic should be initiated before wild type pandemic starts.One reason is to avoid reassortment (mixture) of virus RNA and another is to avoid clinical confusion. It should not overlap with influenza season.
- Nosocomial Infections & Control
Location:
Session Introduction
Goutam Kumar Acherjya
Upazila Health Complex, Bangladesh
Title: Antimicrobial Resistance - A Global Public Health Challenge.
Biography:
Dr. Goutam Kumar Acherjya is working as a junior consultant of Medicine in the Upazila Health Complex, Bagherpara, Jashore, Bangladesh. He has obtained his MBBS degree from Sher-E-Bangla Medical College & Hospital under University of Dhaka, Bangladesh in 2003 and completed Fellowship (FCPS) in internal medicine in 2011 from Bangladesh College of Physician and Surgeon (BCPS), Bangladesh. He has completed Fellowship training under Emeritus Prof. AV Srinivashan in AVS Clinic and Prof. MR Sivakumar in GLB Hospital and Acute Stroke Centre in Chennai, Tamil Nadu, India. He has achieved his Life Membership from Bangladesh Society of Medicine and Bangladesh Medical Association. He has gained his membership from American College of Physician in 2016. He has experience to organize a number of CME, Symposium and Scientific Seminars in the regional, national and international levels. He has delivered several presentations in the prestigious national and international conferences. Recently he has won the Bangladesh Society of Medicine Research Grant Award 2018. One of his abstract has been selected among the top fifty abstracts in the ACP early carrier abstract competition in 2018. He has delivered both oral and poster presentations in the 34th World Congress of Internal Medicine, Cape Town, South Africa in 2018. He has 11 national and international publications and several interesting case reports. Some of his articles are on the way to publish in some eminent national and international journals. He has experience to consult at different levels of Bangladesh Health Sectors. Now he is practicing to consult his private patients in Modern Hospital & Diagnostic Centre, Jashore, Bangladesh. He used to consult both indoor and outdoor patients in his working place. As a researcher his areas of interest are Diabetes, Effect of Metabolic disorders on Central Nervous System and Gerentology.
Abstract:
Over the couple of decades the antimicrobial resistance is one of most common global public health problems not only in the developed countries but also developing countries. In the daily clinical practice antibiotics are commonly prescribed in case of respiratory tract infections, many of the genitourinary tract infections, acute of chronic gastroenteritis or other gastro intestinal symptoms, traumatized patients to prevent secondary infections. Antibiotics are commonly used to prevent and control the bacterial infection for reducing the mortalities and morbidities but its resistance has become the major public health challenge in the era of 21st century. After achieving the millennium development goal, antibiotic resistance will be one of the major stakeholders to set the sustainable developmental goals as the scenario is more endangering and life threatening than our current anticipation. A complex mechanism of interaction between genetic, pathogenic properties, environmental and host factors are related to develop antimicrobial resistance. Out of which several factors including inappropriate antibiotics practicing, patient’s illiteracy, unauthorized sale of antibiotics, inadequate supervision by drug monitoring agencies and non-human use of antibiotics such as animal production are modifiable. Many of the pathogens have shown highly resistance to several commonly used antimicrobials reported in various studies which is really alarming for us. So, the judicious strategies should be planned to prevent and combat against the antimicrobial resistance and make the globe livable for our generation next.
- Vaccines and Vaccination
Location:
- Infection, Immunity and Inflammation
Location:
Session Introduction
Valentina A DÑ–vocha
Lugansk State Medical University,Rubezhnoe, Ukraine
Title: Presence of cellular components in vaccines and immunobiological drugs
Biography:
Abstract:
Now preventive maintenance of a flu by means of vaccination is conventional and is supported by experts of all world. To check presence of trypsin-like proteinase and its inhibitor in antiflu and other vaccines and in immunobiological blood preparations of domestic and foreign manufacture. In work following commercial preparations have been used:" Interferon leukocytic human"," the Immunoglobulin of human placental, donor 10 %, a gonococcal vaccine a herpetic vaccine (Odessa), vaccines for preventive maintenance of a flu, a season 2002/2003 -"Influvac" which consists of hemagglutinins and a neuraminidase of a virus of a flu, strains: Ð/Moscow/10/99 (H3N2), Ð/New Caledonia/20/99 (H/N), B/Hong Kong/330/2001, "Fluarix" which consists of hemagglutinins of Strains (H1N1) A/New Caledonia (H3N2), Ð/Panama and Ð’/Shandont 17/97 and "Vaxigrip" which consists of three Strains of a flu virus, a vaccine for preventive maintenance of a Hepatitis A - "Avaxim", a blood preparation received from a
Heparin (the antifactor of Ha) - "Fraxiparine", a preparation from A blood of calfs for a hemodialysis - "Solcoseryl". Preparations Were investigated before the termination of a period of validity. Resuits.Work is devoted to study presence of components of a Cell-owner and its inhibitor in vaccines and blood preparations And to define presence trypsin-like proteinase and its inhibitor in Vaccines and blood preparations. It is revealed that anti Influenza vaccines (influvac, vaxigrip, fluarix), herpetic and
Tularemic vaccines contained an inhibitor of trypsin-like Proteinase in considerable quantity. Commercial preparations From a human donor blood (an immunoglobulin, interferon, Fraxiparine and solcoseryl) contained as trypsin-like proteinase, And its inhibitor. The immunoglobulin contained in 4,0 times more Inhibitor, than interferon. Conclusions. Hence, the modern vaccines
Applied to prophylaxis and treatment, are insufficiently clear. Presence of cellular components (enzymes and inhibitors) could Lead to allergization and follow complication which is not very Known.